Ultrasound Research Today is a free monthly online journal that collates and summarizes the latest research about Ultrasound, including details on screening, diagnosis, pregnancy, detection.

An efficient and practical synthesis of bis(indolyl)methanes catalyzed by aminosulfonic acid under ultrasound.

Li JT, Dai HG, Xu WZ, Li TS

College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding 071002, PR China. orgsyn@mail.hbu.edu.cn

Synthesis of bis(indolyl)methanes via electrophilic substitution reactions of indoles with aromatic aldehydes and ketones catalyzed by aminosulfonic acid was carried out in 23-96% yield at 30-38 degrees C in EtOH aqueous solution under ultrasound irradiation.

Published 14 October 2005 in Ultrason Sonochem, 13(1): 24-7.
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